Description

Voxzogo For Sale

What is Voxzogo?

Voxzogo (vosoritide) is a C-type natriuretic peptide (CNP) analog that is given by subcutaneous injection and may be used to increase linear bone growth in children with achondroplasia with open bone growth plates (epiphyses). Voxzogo For Sale

Achondroplasia affects endochondral bone growth, which is the process during which growing cartilage is systematically replaced with bone tissue to form the growing skeleton. Endochondral bone growth occurs in over 90% of bones in the body. In children with achondroplasia, bone growth is impaired because of an imbalance in the relationship between fibroblast growth factor receptor 3 (FGFR3) and CNP signaling pathways within the cells of the growth plate. FGFR3 slows bone growth while CNP promotes bone growth. Voxzogo works by stimulating CNP, improving the balance between FGFR3 and CNP, and increasing bone growth in children with open growth plates.

Voxzogo was approved on November 19, 2021, under the accelerated approval criteria for children with achondroplasia with open epiphyses. This criterion is dependent upon continued benefit being shown in clinical trials.

Warnings

May cause a temporary decrease in blood pressure, with symptoms such as dizziness, fatigue, or nausea. Children on antihypertensive medicines may be more at risk. To reduce the risk of low blood pressure, make sure your child is well-hydrated and has had enough food before you administer the infection. Voxzogo For Sale online

Not recommended in children with renal impairment (eGFR <60 mL/min/1.73 m²).

Before giving your child Voxzogo

Before you give your child Voxzogo, tell your child’s healthcare provider about all your child’s medical conditions, including if they have kidney problems or there is a chance they could become pregnant, are pregnant, or are breastfeeding.

How is Voxzogo administered, given, or used?

To reduce the risk of low blood pressure ensure your child:

• Has had adequate food intake before Voxzogo administration
• Drinks approximately 240 to 300 mL (8 to 10 ounces) of fluid in the hour before administration.

The recommended dosage is based on your child’s actual body weight. Your healthcare provider will calculate the dosage and volume to administer for you.

Your healthcare provider will also give you instructions about the right way to store, prepare, and give Voxzogo injections at home. Do not try to inject it until you have been shown the right way to do so.

• Voxzogo is administered under the skin (subcutaneously) of the abdomen once daily.
• Try to inject it at about the same time each day.

Your doctor will monitor and assess your child’s body weight, growth, and physical development regularly every 3 to 6 months and adjust the dosage accordingly.

Voxgogo should be stopped once your healthcare provider has confirmed there is no further growth potential, as indicated by the closure of the growth plates.